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Fig. 4 | BMC Neuroscience

Fig. 4

From: Diazepam and ethanol differently modulate neuronal activity in organotypic cortical cultures

Fig. 4

Relative change in the duration of up-states for a diazepam (DZP) and b ethanol (EtOH). a Diazepam had a strong effect on the duration of up-states when compared versus control conditions (15 µM: (p = 0.031, uncorrected; g = − 0.88 [− 0.43 − 1.77]); 30 µM diazepam (p = 0.11; g = − 1.25 [− 0.54 − 2.75], and p = 0.578 and g = − 0.04 [− 0.80 0.47] for 15 µM vs. 30 µM diazepam. b While 30 mM ethanol had no effect on up-state duration when compared versus control conditions (p = 0.432; g = − 0.14 [− 0.82 0.32]), 60 mM ethanol had a weak, but significant (p = 0.0488, uncorrected) effect (g = 0.40 [− 0.11 1.05]) on up-state duration when compared versus control conditions. Further, 60 mM ethanol had a medium effect causing shorter up-states (p = 0.0195, uncorrected; g = 0.55 [0.28 1.05), when compared against 30 mM ethanol. #p < 0.05 uncorrected; §strong effect

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