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Table 1 Group average plasma concentrations (± SEM) of TSH, CARTp and SAP, in LPS and vehicle-treated controls, with and without indomethacin

From: LPS immune challenge reduces arcuate nucleus TSHR and CART mRNA and elevates plasma CART peptides

 ControlLPSPINDO/controlINDO/LPSP
TSH pg/mL200 ± 61
(n = 6)
181 ± 77
(n = 5)
nsNdNd
CARTp pg/mL647 ± 125
(n = 9)
1428 ± 356
(n = 8)
< 0.05671 ± 130
(n = 3)
4855 ± 1688
(n = 4)
< 0.01
SAP μg/mL3.7 ± 0.5
(n = 12)
12.1 ± 1.6
(n = 13)
< 0.0014.9 ± 0.4
(n = 6)
44.8 ± 4.4
(n = 8)
< 0.001
  1. Student’s t test was used for comparing LPS-injected animals versus the respective control group
  2. n sample size, Nd not done, ns not significant
  3. P < 0.05 was considered significant