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Table 1 Group average plasma concentrations (± SEM) of TSH, CARTp and SAP, in LPS and vehicle-treated controls, with and without indomethacin

From: LPS immune challenge reduces arcuate nucleus TSHR and CART mRNA and elevates plasma CART peptides

 

Control

LPS

P

INDO/control

INDO/LPS

P

TSH pg/mL

200 ± 61

(n = 6)

181 ± 77

(n = 5)

ns

Nd

Nd

–

CARTp pg/mL

647 ± 125

(n = 9)

1428 ± 356

(n = 8)

< 0.05

671 ± 130

(n = 3)

4855 ± 1688

(n = 4)

< 0.01

SAP μg/mL

3.7 ± 0.5

(n = 12)

12.1 ± 1.6

(n = 13)

< 0.001

4.9 ± 0.4

(n = 6)

44.8 ± 4.4

(n = 8)

< 0.001

  1. Student’s t test was used for comparing LPS-injected animals versus the respective control group
  2. n sample size, Nd not done, ns not significant
  3. P < 0.05 was considered significant
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BMC Neuroscience

ISSN: 1471-2202

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