Advertisement
Table 1 Detailed description of items forming the modified neurological severity score (mNSS)
From: The role of PI3K-mediated AMPA receptor changes in post-conditioning of propofol in brain protection
| Motor tests | |
| Raising rat by tail (normal = 0, maximum = 3) | (3) |
| Flexion of forelimb | 1 |
| Flexion of hindlimb | 1 |
| Head moved > 10 degree limb vertical axis within 30 s | 1 |
| Placing rat on floor (normal = 0, maximum = 3) | (3) |
| Normal walk | 0 |
| Inability to walk straight | 1 |
| Circling toward the paretic side | 2 |
| Falling down to paretic side | 3 |
| Sensory tests (normal = 0, maximum = 2) | (2) |
| Placing test (visual and tactile test) | 1 |
| Proprioceptive test (deep sensation, pushing paw against table edge to stimulate limb muscles) | 1 |
| Beam balance tests (normal = 0, maximum = 6) | (6) |
| Balance with steady posture | 0 |
| Grasps side of beam | 1 |
| Huging beam and 1 limb falling down from beam | 2 |
| Huging beam and 2 limbs falling down from beam, or spins on beam (> 60 s) | 3 |
| Attempting to balance on beam but falling of (> 40 s) | 4 |
| Attempting to balance on beam but falling of (> 20 s) | 5 |
| Falling of; no attempt to balance or hang on the beam (< 20 s) | 6 |
| Reflex absence and abnormal movements (normal = 0, maximum = 4) | (4) |
| Pinna reflex (head shaken when auditory meatus is touched) | 1 |
| Corneal reflex (eyes blink when cornea is lightly touched with cotton) | 1 |
| Startle reflex (motor response to brief noise from clapping hands) | 1 |
| Seizures, myoclonus, myodystony | 1 |
| Maximum points | (18) |
