Fig. 1

Visual assessment score (best 0 points, worst 29 points) as an indicator of pain intensity after subarachnoid hemorrhage (SAH, a) and controlled cortical impact (CCI, b). SAH subarachnoid hemorrhage, CCI controlled cortical impact, SHAM sham operation, VEH vehicle solution, BUP buprenorphine, CAR carprofen, MEL meloxicam (Kruskal–Wallis test and Dunn’s multiple comparison test; SAH: N = 25, H = 18.67, P = 0.0009; CCI: N = 50, H = 18.69, P = 0.0009)