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Fig. 3 | BMC Neuroscience

Fig. 3

From: TNF-α antagonist attenuates systemic lipopolysaccharide-induced brain white matter injury in neonatal rats

Fig. 3

Representative photomicrographs of pre-OLs af by immunohistochemistry using PDGFα-R and NG2 and O4+ oligodendrocyte (gi) and TUNEL staining cells jl by immunofluorescence (IF) staining of the cingulum (Bregma − 1.0) on P4. Pre-OLs were attenuated in the L group and preserved in the LE group (p, q). Double-labelling showed that many TUNEL-positive cells were also positive for O4 (mo). O4+ oligodendrocytes were decreased in the L group with increased TUNEL-positive cells in the IF staining, and O4+ oligodendrocytes were recovered in the LE group (rt). ** and *represent significant differences between groups (P < 0.01 and P < 0.05, respectively). ANOVA with a Bonferroni test was conducted. There were six rats per group

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