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Fig. 6 | BMC Neuroscience

Fig. 6

From: Isoliquiritigenin attenuates lipopolysaccharide-induced cognitive impairment through antioxidant and anti-inflammatory activity

Fig. 6

Effects of ISL on GSK-3β activity, NRF2 and NF- κB signaling. ae Western blotting and histograms show the protein levels of nuclear NRF2, total NRF2, nuclear NF-κB and the ratio of p-GSK-3β/GSK-3β in the hippocampus of each group. Lamin B and β-actin were used as a loading control. f Quantitative analysis by qRT-PCR demonstrates the mRNA levels of HO-1 and NQO1 in the hippocampal homogenates. Values are presented as mean ± SEM (n = 6). *p < 0.05 and **p < 0.01 vs. normal group, #p < 0.05 and ##p < 0.01 vs. LPS group

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