Skip to main content

Table 2 Neuropsychological function and hormone levels in patients at baseline and after administered donepezil for 24–26 weeks (n = 21)

From: Higher levels of thyroxine may predict a favorable response to donepezil treatment in patients with Alzheimer disease: a prospective, case–control study

Variables (mean ± SD)

Baseline

Follow up

F(1,18)a/F(1, 20)

p value

η 2p (%)

MMSE scoresa

16.1 ± 5.4

17.1 ± 5.2

0.25

.624

1.4

Cortisol (μg/dl)

10.2 ± 2.9

10.6 ± 1.8

0.45

.511

2.2

Thyrotropin (mIU/l)

1.4 ± 0.9

1.4 ± 1.0

0.42

.523

2.1

Total T3 (ng/dl)

85.5 ± 8.6

81.4 ± 10.1

7.57

.012

27.4

Free T3 (pg/ml)

2.3 ± 0.3

2.2 ± 0.3

1.52

.233

7

Total T4 (μg/dl)

6.4 ± 1.0

5.7 ± 1.0

7.12

.015

26.3

Free T4 (ng/dl)

1.0 ± 0.1

1.0 ± 0.1

0.07

.800

0.3

  1. MMSE Mini–Mental State Examination
  2. aAge and years of education as covariates