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Table 4 Analysis of multiple features of 184 Chinese Sjögren’s syndrome patients with neurological involvement

From: Clinical features and risk factors of neurological involvement in Sjögren’s syndrome

 

pSS

sSS

P value

125

59

Age (years)

52.81 ± 14.95

47.93 ± 16.22

0.084

Sex, female, n (%)

109 (87.20%)

56 (94.90%)

0.126

Disease duration (months)

51.57 ± 66.84

46.07 ± 68.73

0.955

Xerostomia, n (%)

88 (70.40%)

50 (84.70%)

0.036

Xerophthalmia, n (%)

44 (35.20%)

22 (37.30%)

0.783

ESSDAI

7.84 ± 2.83

8.81 ± 3.45

0.129

ESSPRI

2.77 ± 1.34

3.38 ± 1.63

0.038

Liver dysfunction, n (%)

41 (33.60%)

28 (49.10%)

0.047

Articular involvement, n (%)

46 (36.80%)

40 (67.80%)

< 0.001

LSGB, lymphocytic focus ≥ 1

76 (60.80%)

50 (84.70%)

0.001

Saliva gland atrophy

78 (70.30%)

46 (86.80%)

0.021

Albumin levels (g/L)

37.35 ± 5.73

34.12 ± 5.94

< 0.001

Low C3 level (< 0.9 g/L)

54 (46.20%)

36 (65.50%)

0.018

Low C4 level (< 0.1 g/L)

6 (5.30%)

11 (20.80%)

0.005

Antiphospholipid syndrome

0

6(10.17%)

< 0.001

  1. NP neurological, ESSDAI European League Against Rheumatism Sjögren’s syndrome disease activity index, ESSPRI European League Against Rheumatism Sjögren’s syndrome patient reported index, ANA antinuclear antibodies, C3 complement component 3, C4 complement component 4, CRP C-reactive protein, ESR erythrocyte sedimentation rate, LSGB labial salivary gland biopsy, RF rheumatoid factor