Regions | MRI | Histology | ||||||
---|---|---|---|---|---|---|---|---|
FA | MD (×10−5 mm2/s) | T1 (ms) | T2 (ms) | PLP | SMI-312 | CD68 | Ferritin | |
Lateral Corticospinal Tract | 0.17 ± 0.03 | 11.23 ± 1.19 | 714.8 ± 31.4 | 34.2 ± 2.11 | 0.379 | 0.356 | 0.044 | 0.061 |
Normal appearing white matter | 0.19 ± 0.07 | 7.95 ± 2.52 | 672.1 ± 23.6 | 30.9 ± 1.31 | 0.696 | 0.606 | 0.016 | 0.036 |
P value | <Â 0.001 | <Â 0.001 | <Â 0.001 | <Â 0.001 | NA | NA | NA | NA |