Skip to main content

Table 3 Molecular descriptor values of the top interacting antipsychotic drugs

From: In silico repurposing of antipsychotic drugs for Alzheimer’s disease

S. no Name of the drug Molecular weight QPlogPo/w DonorHB accptHB Percent human-oral absorption Violation of Lipinski’s rule
1 Sulmepride 242.031 1.46 1 2 82.403 0
2 Promazine hydrochloride 214.221 − 0.867 4 6.9 53.364 0
3 Bromperidol 223.069 4.368 1 4.75 100 0
4 Anisopirol 358.455 4.047 1 5.45 100 0
5 Melperone 263.354 2.944 0 4 96.488 0
6 Pimozide 461.555 6.413 1 4 96.301 1
7 Benperidol 381.449 3.45 1 6 86.914 0
8 Azabuperone 290.38 1.905 0 6 79.665 0
9 Anisoperidone 335.445 4.126 0 4.75 100 0