Table 3 Molecular descriptor values of the top interacting antipsychotic drugs
From: In silico repurposing of antipsychotic drugs for Alzheimer’s disease
S. no | Name of the drug | Molecular weight | QPlogPo/w | DonorHB | accptHB | Percent human-oral absorption | Violation of Lipinski’s rule |
|---|---|---|---|---|---|---|---|
1 | Sulmepride | 242.031 | 1.46 | 1 | 2 | 82.403 | 0 |
2 | Promazine hydrochloride | 214.221 | − 0.867 | 4 | 6.9 | 53.364 | 0 |
3 | Bromperidol | 223.069 | 4.368 | 1 | 4.75 | 100 | 0 |
4 | Anisopirol | 358.455 | 4.047 | 1 | 5.45 | 100 | 0 |
5 | Melperone | 263.354 | 2.944 | 0 | 4 | 96.488 | 0 |
6 | Pimozide | 461.555 | 6.413 | 1 | 4 | 96.301 | 1 |
7 | Benperidol | 381.449 | 3.45 | 1 | 6 | 86.914 | 0 |
8 | Azabuperone | 290.38 | 1.905 | 0 | 6 | 79.665 | 0 |
9 | Anisoperidone | 335.445 | 4.126 | 0 | 4.75 | 100 | 0 |