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Table 1 Activations for whole sample of all subjects

From: From provocation to aggression: the neural network

Brain areas L/R X Y Z T p-value Cluster size
(MNI coordinates)
Aggression after high provocation > aggression after low provocation
 Medial prefrontal cortex (mPFC) + rostral anterior cingulate cortex (rACC) + orbitofrontal cortex (OFC) R 10 32 54 6.48 <.001 5323
 Anterior angular gyrus (part of inferior parietal gyrus) R 52 – 54 40 4.64 < .001 668
 Insula L – 30 20 – 18 5.44 < .001 397
 Dorsolateral prefrontal cortex (dlPFC) + ventrolateral prefrontal cortex (vlPFC) R 56 28 20 5.57 < .001 277
Aggression after low provocation > aggression after high provocation
 No suprathreshold activations
High provocation > low provocation
 rACC + mPFC R/L 14 40 2 5.54 < .001 819
 Thalamus R/L 10 2 – 2 5.60 < .001 792
Low provocation > high provocation
 No suprathreshold activations
  1. Activation cluster of all subjects, p < 0.001 and cluster-level p(FWE-corrected) < 0.05