Fig. 2

Mean ± SEM responses in the optokinetic nystagmus test of visual function and immunoreactivity of axonal and oligodendrocyte proteins, 3 days following partial transection of the optic nerve. a Total number of smooth pursuits and fast resets/minute engaged in the task by normal, or injured vehicle or inhibitor treated animals. b Effects of injury ± combinations of ion channel inhibitors on ratio of Tau p[S³⁹⁶] to total Tau and c ratio of Tau p[T²⁰⁵] to total Tau immunoreactivities were calculated using mean ± SEM area above an arbitrarily set threshold for each protein. Similarly, d mean ± SEM area above threshold of acetylated tubulin, e NogoA and f mean ± SEM intensity above threshold of MBP immunoreactivity. Significant differences compared to vehicle are indicated by *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001