Fig. 7
ETA receptor overexpression increases cell death in primary RGCs. a Representative images of dead (red) and total (blue) RGCs following transduction with either AAV-2-GFP or AAV-2-ETA and 24 h treatment with 100 nM ET-1 or ET-3. Positive control shows RGCs treated with methanol. b Quantitative analysis of percent cell death of RGCs. Bars represent mean ± SEM (n = 3). Asterisks indicated statistical significance *p < 0.05, ****p < 0.0001 by one-way ANOVA and Tukey’s post hoc test