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Fig. 7 | BMC Neuroscience

Fig. 7

From: Identifying the appropriate time for deep brain stimulation to achieve spatial memory improvement on the Morris water maze

Fig. 7

Effects of time-dependent MS-DBS on adult hippocampal neurogenesis. a Representative immunofluorescence images reveal the effects of time-dependent MS-DBS on neurogenesis and differentiation. Hippocampal dentate gyrus (DG) sections stained for Sox2 (red), DCX (green), and DAPI (blue) are shown. The number of Sox2- (b) and DCX-immunopositive cells (c) was significantly lower in the lesion and probe-stimulation groups than in the normal group. However, the numbers of Sox2- and DCX-immunopositive cells were elevated in the pre- and training-stimulation groups (values represent the mean ± SEM, p < 0.05)

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