Fig. 4From: Paclitaxel causes degeneration of both central and peripheral axon branches of dorsal root ganglia in miceMacrophages infiltration along degenerated axons in nerve intoxicated with paclitaxel. Longitudinal frozen sectioned nerve segment stained for CD68 and MBP. a MBP staining of nerve segment intoxicated with paclitaxel. The vast majority of fibers appear normal with the exception of a single fiber that show degenerated myelin (arrow). b CD68 staining. Macrophages (CD68-positive cells) infiltrate along a degenerating fiber, while not associating with other normal fibers (arrow). c Merged image of a and b. Scale bar 50 μmBack to article page