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Table 1 Patient characteristics

From: Impact of cognitive stimulation on ripples within human epileptic and non-epileptic hippocampus

Subject

Gender

Age at SEEG

FS

Age at Seizure onset

MRI before SEEG

Type and side of epilepsy

SOZ

Intervention/histopathology

Postoperative outcome (follow-up)

Number of analyzed hippocampal contacts

1

F

28

13

Meningoencephalocele and hypotrophy of left temporal pole

TLE/L

Left temporopolar region

AMTR and plastic surgery of skull base

Seizure-free (3 years)

3 (E)

2

F

23

13

Local atrophy and gliosis in the horn of left lateral ventricle after exstirpation of pilocystic astrocytoma within parieto-occipital region

ETLE/L

Left parieto-occipital bounder and occipital lobe

Reoperation: lesionectomy/reparative changes after exstirpation of astrocytoma

Seizure-free (1 year)

3 (N)

3

F

37

17

Normal

TLE/R

Right hippocampus

AMTR/FCD

Seizure-free (3 years)

8 (E)

4

M

35

23

Normal

TLE/R

Right hippocampus

AMTR/normal

Improved (2.5 years)

5 (E), 5 (N)

5

F

33

+

5

Normal

TLE/R

Right hippocampus and temp. pole

AMTR/FCD

Improved (1.5 years)

5 (E), 3 (N)

6

F

25

6

Susp. cortical dysplasia TPO left

ETLE/L

Left lateral tempo–parieto–occipital region

Focal cortectomy/normal

Not improved (2 years)

3 (N)

7

M

47

+

6

Slight atrophy of right hippocampus

ETLE/R

Right lateral parieto-occipital region

VNS/–

Non-responder (1.5 years)

7 (N)

8

M

35

28

MTS left

TLE/L

Left hippocampus

AMTR/gliosis

Improved (3 years)

2 (E), 6 (N)

9

F

28

3.5

normal

ETLE/R

Multifocal frontal

VNS/–

Responder (1 year)

3 (N)

10

F

20

16

Left temporal pole resection due to epilepsy

TLE/bilat

Left and right hippocampus (independ.)

VNS/–

Non-responder (1 year)

8 (E)

  1. SEEG stereoelectroencephalography, FS febrile seizures, SOZ seizure onset zone, MTS mesiotemporal sclerosis, TPO temporo–parieto–occipital, TLE tempoval lobe epilepsy, ETLE extratemporal lobe epilepsy, R right, L left, AMTR anteromesial temporal resection, VNS vagal nerve stimulation, FCD focal cortical dysplasia, (E) epileptic, (N) non-epileptic.