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Figure 4 | BMC Neuroscience

Figure 4

From: Disrupting monotony during social isolation stress prevents early development of anxiety and depression like traits in male rats

Figure 4

Estimation of serotonin (5-HT) and 5-hydroxy indole acetic acid (5-HIAA) by HPLC. i) Representative chromatograms showing the peaks for serotonin (5-HT), (ii) representative chromatograms showing the peaks for 5-HIAA, graph showing (iii) changes in the level of 5-HT and (iv) changes in the level of 5-HIAA in hippocampus following exposure to monotony stress, PCPA administration and novel object intervention during isolation. Values are expressed as mean ± SEM. ‘a’ denotes p ≤ 0.01 when compared to PHNO group, ‘b’ denotes p ≤ 0.01 when compared to PH, ‘c’ denotes p ≤ 0.01 when compared to PHNOPCPA group, ‘d’ denotes p ≤ 0.01 when compared to PHPCPA group and ‘e’ denotes p ≤ 0.01 when compared to SH group and ‘f’ denotes p ≤ 0.01 when compared with SHNO group.

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