Protein expression of inflammatory cytokines and iNOS was decreased in MCAO rat brains following treatment with E, S and E + S. The expression levels of TNF-α, IL-1β and iNOS in MCAO rat brains are depressed significantly at 3 days following treatment with E, S and E + S when compared with the MCAO ( n = 5 for each group). Significant differences in protein levels between MCAO and drugs used rats are expressed as *p <0.01. TNF-α protein expression level of the E + SH group was most drastically suppressed following MCAO when compared with the other groups. Significant difference is expressed as #p <0.05. The values represent the mean ± SD in triplicate.