Cytokine profile in direct co-cultures with tMNC, CD133+and CD133- on Day 3. Control: sum of cytokine concentration from single cultured (grey) post-hypoxic SH-SY5Y cells and HUCB-MNC (light green = tMNC, light red = CD133-, not detectable = CD133+). Co-culture: direct co-culture of post-hypoxic SH-SY5Y cells and HUCB-MNC (dark green = tMNC, dark red = CD133-, dark yellow = CD133+). Data are derived from four independent experiments and are expressed as pg/ml. * significant differences in cytokine concentrations of co-cultures compared to control cultures. Note different axis scaling.