Figure 4

Statistical summary of anatomically classified evoked synaptic responses. A) Representative IPSC trace averages (n = 10 repeats) are shown based on the location of stimulating electrode placement: distal apical (top and second from top), proximal apical (third from top) and basal (bottom). B) Box plots show the first and third quartiles around the median with the notch signifying 95% of the median for each sample population (distal apical, n = 18; proximal apical, n = 21; basal, n = 22) and dashed lines indicate the whiskers (1.5× inter-quartile range) and crosses indicate outliers. Rise time estimates are shown summarized by the box plot for distal (median = 4.6 ms), proximal (median = 2.6 ms) and basal (median = 3.8 ms) responses. C) Decay time (τ₁) estimates from the double-exponential fits to the IPSCs evoked from stimulation distally (median = 22 ms), proximally (median = 14 ms) or basally (median = 21 ms). D) Population summary of the total duration (rise time + decay time (τ₁)) estimates are shown for responses evoked distally (median = 27 ms), proximally (median = 17.7 ms) and basally (median = 24 ms). Proximal stimulation produced short duration IPSCs, while distal and basal IPSCs contained a mixture of slow and fast IPSCs with greater range and variability (quartile difference (third-first) = 12 ms, 9 ms and 24 ms for distal, proximal and basal respectively).