Table 2 Wheel running did not ameliorate the effects of the HD mutation on body and brain weight at 9 months of age. The HD transgene affected both body weight (P < 0.001) and brain weight (P < 0.001) at 9 months of age, relative to WT littermates. NE: non-enriched (standard housed); RW: running-wheel housed.

From: Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease