A quantitative method to assess extrasynaptic NMDA receptor function in the protective effect of synaptic activity against neurotoxicity

Table 1 Current and Ca²⁺ responses in the vehicle and AP bursting groups were equivalent.

Charge transfer and area under the curve (AUC) were calculated from the integral of the trace between the current response onset and return to baseline and between the Ca²⁺ response onset and a point 10 min later. Current data comes from 9 vehicle and 10 AP bursting neurons of which Ca²⁺ data was recorded in 5 vehicle and 6 AP bursting cells. All Ca²⁺ analysis was performed from a somatic region of interest.

ISSN: 1471-2202