Figure 6

Venn diagram of gene expression profiles as a function of age. Comparisons between data sets from wild-type and PPT1 knockout mice at 3, 5 and 8 months of age were made and probe sets having p-values of less than 0.005 (two sample t-tests, random variance version) were considered significant. The resulting gene lists were further used to construct a Venn diagram (in GeneSpring) [57] to identify genes potentially uniquely expressed at the three different ages. Complete gene lists are available in Additional Files 4, 5, and 6.