Figure 3

The decrease of glutamine formation in the supernatant of astroglial cells incubated with gp 120 is reversed by NAC. Treatment of astroglial cells with gp 120 (10 nM) for 24 hours produced a reduction of glutamine formation compared with untreated control. NAC (0.5–1 and 5 mM) in pre-treatment of two hours, reversed this effect. Data represent the mean ± S.E.M. of five independent experiments.* P < 0.05 when compared to control; § P < 0.05 treated vs gp 120 treated cells. Statistical analysis was done using ANOVA followed by Student-Newman-Keuls test.