Anxiety-related behaviours observed in the dark/light box. Expression of dnCaMKIV in the NAc increased anxiogenic behaviour during dark/light emergence test performance. Time spent in the lit compartment, emergence frequency and rearing were significantly reduced in dnCaMKIV animals compared to rAAV-empty infused controls (EMPTY) (dnCaMKIV: n = 11, EMPTY: n = 11; p < 0.05 is indicated by asterisks). Means ± S.E.M. are shown.