Chemosensory properties of murine nasal and cutaneous trigeminal neurons identified by viral tracing

BMC Neuroscience

Table 1 Electrophysiological analysis of infected neurons. Electrophysiological characterization of traced nasal, cutaneous, in vitro infected (iv infected), and uninfected (control) TGNs revealed no significant differences. APs: Action potentials

	control TGNs	iv infected TGNs	nasal TGNs	cutaneous TGNs	control TGNs	iv infected TGNs	nasal TGNs	cutaneous TGNs
	Membrane potential/mV				Width of AP at 75 % of amplitude/ms
n	111	78	20	17	94	42	14	13
mean	-56,0	-54,3	-55,0	-54,4	2,27	2,26	1,96	2,40
SD	8,1	10,6	9,7	6,9	0,96	1,19	0,86	0,95
SEM	0,8	1,2	2,2	1,7	0,10	0,18	0,23	0,26
range	38	66	33	23	4,60	5,40	3,00	3,40
	Threshold for activation of VGSCs/mV				Maximal amplitude of APs due to current injection/mV
n	106	45	12	14	95	42	14	14
mean	-32,9	-32,5	-33,0	-31,5	41,3	36,8	37,9	51,3
SD	9,6	11,1	11,3	12,2	16,3	15,3	15,3	10,3
SEM	0,9	1,7	3,3	3,3	1,7	2,4	4,1	2,8
range	60	60	40	36	73	69	48	36,0
	Maximal amplitude (overshoot) of APs/nA				Ih current (-130 mV)/pA
n	12	10	16	14	67	14	7	10
mean	-3,80	-5,22	-3,78	-7,2	-258	-226	-327	-130
SD	1,95	2,74	2,69	3,21	221	205	325	109
SEM	0,56	0,87	0,67	0,86	27	55	123	35
range	6,25	7,49	9,24	12,07	1066	639	845	363
	Threshold of current injection for eliciting APs/pA				Amplitude of "sag"/mV
n	95	42	14	n.d.	11	18	8	3
mean	258	237	213	n.d.	10,1	18,6	22,6	17,0
SD	246	201	202	n.d.	6,2	10,5	15,6	8,0
SEM	25	31	54	n.d.	1,9	2,5	5,5	4,6
range	990	800	770	n.d.	17	37	44	16,0
	Membrane potential due to current injection eliciting APs/mV				Threshold of current injection for Ih-activation/mV
n	94	42	14	14	11	18	8	3
mean	-30,1	-31,5	-34,6	-32,9	-79,5	-83,4	-81,9	-87,3
SD	8,1	10,5	7,9	7,8	7,6	20,4	10,3	7,5
SEM	0,8	1,6	2,1	2,1	2,3	4,8	3,7	4,3
range	54	46	29	27	26	83	31	15

ISSN: 1471-2202