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Table 6 Intermolecular interaction between estrogens and ERα. avan der Waals energy; belectrostatic energy.

From: Select estrogens within the complex formulation of conjugated equine estrogens (Premarin®) are protective against neurodegenerative insults: implications for a composition of estrogen therapy to promote neuronal function and prevent Alzheimer's disease

Estrogens Intermolecular Energy H-Bond Distance
  VDWa Electb Total d1 (Glu353:OE2) d2 (His524:ND1)
17β-estradiol -55.06 -20.43 -75.48 1.56 2.02
Equilin -58.17 -12.33 -70.49 1.71  
Δ8,9-dehydroestrone -58.40 -13.09 -71.49 1.67  
Estrone -55.92 -12.76 -68.68 1.66