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Figure 9 | BMC Neuroscience

Figure 9

From: Equine estrogens differentially inhibit DNA fragmentation induced by glutamate in neuronal cells by modulation of regulatory proteins involved in programmed cell death

Figure 9

Effect of various concentrations of Δ8,17β-estradiol on Bcl-2 and Bax protein levels in HT22 cells treated with 7–8 mM glutamate for 8 h. Western blots are shown on the upper right hand corner and the bars depict densitometry analysis. Note that the glutamate-induced changes (cell death) in Bcl-2 and Bax are reversed in the presence of Δ8,17β-estradiol. a = P < 0.05 vs untreated control cells. b = P < 0.05 vs glutamate alone treated cells.

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BMC Neuroscience

ISSN: 1471-2202

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