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Figure 1 | BMC Neuroscience

Figure 1

From: ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes

Figure 1

Patterns of mitochondrial vacuoles. (A) a small outer membrane bud (arrow); (B-D) enlargement of the buds (arrows) and expansion of the intermembrane space; (E) further separation of outer and inner membrane and intermembrane space expansion; (F-I) patterns of mature vacuoles. Unfilled arrowheads in D-I mark the vacuolar membrane. Large arrows in F-I indicate remnants of inner membrane. Small arrows in D and I indicate broken areas of vacuolar membrane. Small unfilled arrows in H and I point to vesicular membranous elements within the vacuoles. Arrowheads in D and F indicate dendritic membranes.

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BMC Neuroscience

ISSN: 1471-2202

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