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Figure 4 | BMC Neuroscience

Figure 4

From: Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

Figure 4

Decreasing AGRP levels by pSUPER-AGRPi construct decreases body weight (a) Mice transfected with the pSUPER-AGRPi construct shows persistent loss of body weight after transfection while the mice transfected with the control vector recover body weight over a course of six days (n = 14; p < 0.0001). (b) pSUPER-RNAI targeted to AGRP has no effect on mean daily food intake (n = 14; p = 1.6992).

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