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Table 2 Gene Set Enrichment Analysis (GSEA) results

From: Fetal asphyctic preconditioning alters the transcriptional response to perinatal asphyxia

Time of sacrifice Gene set name Description NES FDR q-value Direction Experimental group
6 h KEGG:04141 Protein processing in endoplasmatic reticulum 2.54 <0.001 PA and FAPA
  PF01352 KRABbox 2.42 <0.001 FAPA
  PF00956 Nucleosome assembly protein 2.14 <0.01  
  KEGG:00970 Aminoacyl-tRNA biosynthesis 2.47 <0.001  
  KEGG:00510 N-glycan biosynthesis 2.04 <0.01  
  KEGG:00100 Steroid biosynthesis -2.58 <0.001  
96 h GO:0005746 Mitochondrial respiratory chain -2.20 <0.01 PA and FAPA
  KEGG:00190 Oxidative phosphorylation -2.34 <0.001  
  GO:0001505 Regulation of neurotransmitter levels -2.22 <0.01 PA
  GO:0007268 Synaptic transmission -2.11 <0.01  
  GO:0007269 Neurotransmitter secretion -2.23 <0.01  
  KEGG:04020 Calcium signaling pathway -1.97 <0.01  
  KEGG:04970 Salivary secretion -2.16 <0.01  
  KEGG:04971 Purine metabolism -2.04 <0.01  
  PF00089 Trypsin 2.23 <0.01 FAPA
  GO:0019208 Phosphatase regulator activity -2.09 <0.01  
  KEGG:03010 Ribosome -2.237 <0.001  
  BIOCARTA_PGC1APATHWAY -2.09 <0.01  
  1. Significantly enriched gene sets found with GSEA using the FDR q-value <0.01 as cut-off for significance. NES = Normalized Enrichment Score. FDR q-value = False Discovery Rate method of correction for multiple testing. (PA: experimental group only subjected to perinatal asphyxia. FAPA: experimental group subjected to both fetal preconditioning and perinatal asphyxia).