Table 3 The allelic-wise analysis with a test for trend for the effect of MAPT rs242562 and GSK3B rs334558 on risk for PD
From: MAPT rs242562 and GSK3B rs334558 are associated with Parkinson’s Disease in central China
Number of minor alleles | Cases | Controls | Crude OR (95% CI) | P value | Adjusted OR (95% CI)* | P* value |
|---|---|---|---|---|---|---|
rs242562 | ||||||
0 | 36 | 64 | 1.000 | 1.000 | ||
1 | 116 | 107 | 1.927(1.186,3.132) | 0.008 | 1.892(1.154,3.102) | 0.011 |
2 | 56 | 60 | 1.659(0.960,2.868) | 0.070 | 1.628(0.931,2.846) | 0.087 |
Test for trend | 1.262(0.964,1.651) | 0.091 | 1.250(0.950,1.646) | 0.111 | ||
rs334558 | ||||||
0 | 74 | 97 | 1.000 | 1.000 | ||
1 | 112 | 136 | 1.079(0.729,1.598) | 0.702 | 1.051(0.704,1.570) | 0.807 |
2 | 25 | 29 | 1.130(0.611,2.089) | 0.697 | 1.091(0.583,2.039) | 0.785 |
Test for trend | 1.068(0.806,1.415) | 0.647 | 1.047(0.785,1.395) | 0.756 |