Figure 1

Cholinesterase activity after soman and HI-6 treatment. Cholinesterase activity in the rat plasma, RBC, cerebral cortex and cerebellum (A), at 30 min, 2.5 h, 1, and 7 days after soman (105 μg/kg, s.c) exposure. Efficacy of HI-6 pretreatment (50 mg/kg, i.m, 30 min prior to soman exposure) on soman inhibited cholinesterase activity of rat plasma, RBC, cerebral cortex and cerebellum (B) at 30 min, 2.5 h, 1, and 7 day time points. AChE activity was presented as a percentage of control (n = 4 per each time point). *Significantly different from control. A difference of p < 0.05 was considered significant.