Block Diagram of the implemented neuronal spike statistical analysis. The raw neural spikes are divided into two groups, evoked activity and spontaneous activity, respectively stimulated and non-stimulated experimental sessions. Then the raw spikes were divided into time windows and averaged across repetitions. The average spontaneous activity was subtracted from the average evoked activity and fed into the False discovery Rate (FDR) statistical analysis technique. The output of the FDR is the significant stimulus-response pairs. Using these significant pairs we computed their average connection lengths and the number of supernodes.