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Table 1 Physiological parameters before and after saline or quinpirole administration to unanesthetized rats

From: D2-like receptor activation does not initiate a brain docosahexaenoic acid signal in unanesthetized rats

 

Saline (n = 6)

Quinpirole (n = 7)

 

Before

After

Before

After

Body weight (g)

336 ± 22

 

331 ± 13

 

Rectal temperature (°C)

36.5 ± 1.0

37.1 ± 0.2

37.2 ± 0.3

36.6 ± 0.1**

Heart rate (beats/min)

434 ± 36

393 ± 50

441 ± 22

444 ± 20

Arterial blood pressure (mm Hg)

    

Systolic

182 ± 19

164 ± 33

182 ± 7

178 ± 13

Diastolic

102 ± 13

88 ± 25

104 ± 6

95 ± 14

Number of rats with orofacial activity1

0/6

0/6

0/7

7/7

  1. 1Orofacial activity, consisting of head tremors and sniffing was observed for 10 minutes after saline or quinpirole injection. All quinpirole-treated rats exhibited characteristic head tremors and sniffing activity within 2 minutes of drug injection. Values are mean ± SD of n = 6 saline and 7 quinpirole treated rats per group. **P < 0.01 compared to before quinpirole injection by paired t-test.
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BMC Neuroscience

ISSN: 1471-2202

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