Table 2 Top pathways, networks and molecular and cellular functions identified by pathway analysis using the Cadherin family genes affected by olanzapine
Top canonical pathways | P-value | Number of molecules/ratio* |
|---|---|---|
Gα12/13 Signalling | 9.16E-08 | 5/113 (0.044) |
RhoGDI Signalling | 4.76E-07 | 5/166 (0.03) |
Signalling by Rho Family GTPases | 2.22E-06 | 5/221 (0.023) |
Wnt/β-catenin Signalling | 1.25E-02 | 2/158 (0.013) |
Thyroid Cancer Signalling | 4.16E-02 | 1/40 (0.025) |
Molecular and Cellular Functions | ||
Cell-to-cell Signalling and interaction | 6.13E-04 - 3.01E-02 | 4 |
Cellular movement and development | 1.09E-03 - 2.37E-02 | 4 |
Physiological System Development and Function | ||
Behaviour, tissue development, nervous system development and function | 6.13E-04 - 9.76E-03 | 5 |
Top Networks | ||
Cellular Movement, Cellular Growth and Proliferation, Cancer | 5 |