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Figure 1 | BMC Neuroscience

Figure 1

From: Modelling homeostatic control of high-frequency post-synaptic transmission and its effect on metabolic efficiency in the auditory brainstem

Figure 1

The NO-mediated conductance state (B) improves transmission ratios at 800 Hz compared to the naïve state (A). Blue circles represent Poisson synaptic input and red triangles represent a successfully evoked AP. The lower panels show the Nav, Kv2 and Kv3 currents during an AP, with the charge overlap in cyan. The area under the cyan curve is used as a measure of AP metabolic efficiency [3] and is higher in the NO-mediated case (D) compared to the naïve (C), thus rendering it less efficient.

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