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Table 2 Effect of glucose on the cell cycle of NSCs following in vitro ischemia (n = 6, mean ± SD)

From: High glucose induces apoptosis and suppresses proliferation of adult rat neural stem cells following in vitro ischemia

Glucose (mM)

PI

P

SPF

P

17.5

0.665 ± 0.142

-

0.515 ± 0.014

-

27.75

0.595 ± 0.026

0.002

0.465 ± 0.042

0.016

41.75

0.382 ± 0.019

0.000

0.273 ± 0.024

0.000

83.75

0.217 ± 0.042

0.000

0.176 ± 0.008

0.000

F

333.252

 

239.024

 

P

0.000

 

0.000

 
  1. Proliferation Index (PI) = (S + G2/M)/(G0/G1+ S + G2/M), S-phase cell Fraction (SPF) = S/(G0/G1 + S + G2/M). The data are expressed as the mean ± SD of six independent experiments, and analyzed by one-way ANOVA followed by Bonferroni test versus the normal glucose group (17.5 mM glucose).
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BMC Neuroscience

ISSN: 1471-2202

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