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Figure 7 | BMC Neuroscience

Figure 7

From: The effects of different doses of estradiol (E2) on cerebral ischemia in an in vitro model of oxygen and glucose deprivation and reperfusion and in a rat model of middle carotid artery occlusion

Figure 7

The infarct volume in rats exposed to ischemia–reperfusion injury by MCAO receiving different doses of E2. (A) The OVX group resulted in larger infarct volume compared to the control group. 6 μg/kg and 20 μg/kg E2 replacement significantly decreased the infarct volume. 50 μg/kg E2 replacement group resulted in larger infarct volume than the control group and 6 μg/kg or 20 μg/kg E2 replacement group. (**p < 0.01 v.s. the control group, #p < 0.05 v.s. the OVX group, *p < 0.05 v.s. the control group and 6 μg/kg or 20 μg/kg E2 replacement group). (B) Representative photographs showing infarct volume in the different groups after the MACO.

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BMC Neuroscience

ISSN: 1471-2202

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