Figure 4

Doublecortin-immunoreactive (DCX+) cells in different cortical areas from Pb exposure (right panels) and age-matched control (left panels) groups surviving 6 months. A dramatic loss of DCX + cells occur in the Pb-treated relative to control animals over that parietal (A, B), temporal (C, D) and frontal (E, F) cortex. Scale bar in panel A = 200 μm applying to main panels, equivalent to 100 μm for enlarged inserts.