Figure 5
Protein levels of (A) synaptophysin, (C) drebrin and (E) PSD-95 (with representative immunoblots) in control, low- and high-dose LPS rat brain. Data are ratios of optical densities of protein to β-actin, expressed as percent of control and were compared using one-way ANOVA, mean ± SEM (n = 8). mRNA levels of (B) synaptophysin and (D) drebrin in control, low- and high-dose LPS in rat brain, measured using real time RT-PCR. Data are normalized to the endogenous control (β-globulin) and relative to control level (calibrator), using the ΔΔCT method. Comparisons between LPS groups were made using one-way ANOVA, mean ± SEM (n = 8), *p < 0.05, ***p < 0.001.