Skip to main content

Table 8 Results of 5-HT1A mRNA and SERT levels in the hippocampus and hypothalamus of foetuses

From: Pre-gestational stress reduces the ratio of 5-HIAA to 5-HT and the expression of 5-HT1A receptor and serotonin transporter in the brain of foetal rat

Groups

n

Position

5-HT1A mRNA(× 10-2)

SERT

Female foetuses of control

47

Hippocampus

0.284 ± 0.051

0.312 ± 0.069

   

(0.269~0.299)

(0.292~0.332)

  

Hypothalamus

0.272 ± 0.031

0.342 ± 0.059

   

(0.263~0.281)

(0.325~0.359)

Female foetuses of CUS

43

Hippocampus

0.223 ± 0.036**

0.213 ± 0.06**

   

(0.212~0.234)

(0.194~0.232)

  

Hypothalamus

0.266 ± 0.059

0.246 ± 0.037**

   

(0.248~0.284)

(0.234~0.258)

Male foetuses of control

40

Hippocampus

0.288 ± 0.051

0.334 ± 0.042

   

(0.272~0.304)

(0.320~0.348)

  

Hypothalamus

0.265 ± 0.044

0.351 ± 0.046

   

(0.251~0.279)

(0.336~0.366)

Male foetuses of CUS

49

Hippocampus

0.233 ± 0.042**

0.226 ± 0.034**

   

(0.221~0.245)

(0.216~0.236)

  

Hypothalamus

0.275 ± 0.028

0.235 ± 0.055**

   

(0.267~0.283)

(0.219~0.251)

  1. Data are mean ± S.D. Data in bracket are 95% confidence intervals for each relevant statistic. 5-HT1A mRNA levels are the relative level of 5-HT1A to GAPDH. SERT levels are the relative level of SERT to β-actin. **: P < 0.01 compared with control by the same sex and the same position