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Table 8 Results of 5-HT1A mRNA and SERT levels in the hippocampus and hypothalamus of foetuses

From: Pre-gestational stress reduces the ratio of 5-HIAA to 5-HT and the expression of 5-HT1A receptor and serotonin transporter in the brain of foetal rat

Groups n Position 5-HT1A mRNA(× 10-2) SERT
Female foetuses of control 47 Hippocampus 0.284 ± 0.051 0.312 ± 0.069
    (0.269~0.299) (0.292~0.332)
   Hypothalamus 0.272 ± 0.031 0.342 ± 0.059
    (0.263~0.281) (0.325~0.359)
Female foetuses of CUS 43 Hippocampus 0.223 ± 0.036** 0.213 ± 0.06**
    (0.212~0.234) (0.194~0.232)
   Hypothalamus 0.266 ± 0.059 0.246 ± 0.037**
    (0.248~0.284) (0.234~0.258)
Male foetuses of control 40 Hippocampus 0.288 ± 0.051 0.334 ± 0.042
    (0.272~0.304) (0.320~0.348)
   Hypothalamus 0.265 ± 0.044 0.351 ± 0.046
    (0.251~0.279) (0.336~0.366)
Male foetuses of CUS 49 Hippocampus 0.233 ± 0.042** 0.226 ± 0.034**
    (0.221~0.245) (0.216~0.236)
   Hypothalamus 0.275 ± 0.028 0.235 ± 0.055**
    (0.267~0.283) (0.219~0.251)
  1. Data are mean ± S.D. Data in bracket are 95% confidence intervals for each relevant statistic. 5-HT1A mRNA levels are the relative level of 5-HT1A to GAPDH. SERT levels are the relative level of SERT to β-actin. **: P < 0.01 compared with control by the same sex and the same position
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