Effects of ATX on MPP+-induced NOX2, NRF2 and HO-1 levels in PC12 cells. The groups are C: Control; M: MPP+ (500 μM); M+A: MPP+ (500 μM) plus ATX (10 μM); MAS: MPP+ (500 μM) plus ATX (10 μM) and SnPPIX (10 μM); MD: MPP+ (500 μM) plus DPI (1 μM), A: ATX (10 μM). (A). The protein expression of Nox2, NRF2 and HO-1 was determined by western blot analysis; (B). NOX2 and HO-1 mRNA levels were determined by quantitative real-time PCR.