Figure 2

Infarct sizes were decreased in FLAP knockout mice. In terms of mortality-adjusted median infarct size, the knockout animals were protected from focal cerebral ischemia in comparison to their wild type counterparts (p < 0.0005). Infarct size is presented in mm³. The segments of the box plots depict the 10^th, 25^th, 50^th, 75^th and 90^th percentile. The boxes above the box plots represent the mortality in the two groups. WT = Wild type group, KO = FLAP knockout group.