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Table 1 Plasma glucose, insulin and triglyceride concentrations, calculated HOMA index and whole blood ß-hydroxybutyrate concentrations at 4 and 8 weeks of feeding control or high-sucrose diet

From: Upregulated expression of brain enzymatic markers of arachidonic and docosahexaenoic acid metabolism in a rat model of the metabolic syndrome

 

4 weeks

8 weeks

   

Parameter

Control

High-sucrose

Control

High-sucrose

Time

Diet

Time x Diet

Glucose (mmol/L)

4.0 ± 0.41

4.4 ± 0.1

4.1 ± 1.0

6.0 ± 1.8***

<0.05

<0.01

 

Insulin (ng/ml)

0.6 ± 0.4

0.3 ± 0.1

0.7 ± 0.3

1.8 ± 0.9**

<0.001

 

<0.05

HOMA1 index

2.3 ±1.91

1.4 ± 0.41

4.1 ± 4.1

10.5 ± 4.8**

<0.001

<0.05

<0.05

Triglycerides (mg/ml)

0.9 ± 0.2

0.7 ± 0.2

0.7 ± 0.3

1.5 ± 0.5**

<0.05

<0.05

<0.01

β-hydroxybutyrate (mmol/L)

0.9 ± 0.2

0.9 ± 0.2

0.6 ± 0.2

0.7 ± 0.11

<0.05

  
  1. Values are means ± SD (n = 8) 1n=7 due to insufficient sample. 1n=7 due to insufficient sample. Data were analyzed by two-way repeated measures ANOVA, followed by a one-way ANOVA and Bonferroni’s post-hoc test comparing high-sucrose versus controls at 4 and 8 weeks. **p < 0.01; ***p < 0.001 indicates significant difference compared to 8-week control mean.