Figure 1
From: Calcium signals in the nucleus accumbens: Activation of astrocytes by ATP and succinate
Cx43 is present in GFAP-containing astrocytes in the NAc. A: Cx43 immunoreactivity in a coronal section of a PFA-fixed rat brain shows relatively high intensity in the NAc, as compared to adjacent brain regions. Abbreviations: ac - anterior commissure, CP caudate-putamen, LS - lateral septal nucleus, LV - lateral ventricle, NAc - nucleus accumbens, VP - ventral pallidum. Scale bar: 1 mm. B: Comparison of the appearance of Cx43 (red) and GFAP (green) proteins in the NAc. Low magnification (scale bar: 400 μm) confocal photomicrograph of a double labelled section of a PFA-fixed rat brain. Co-localization (yellow) of Cx43 (red) and GFAP (green) immunoreactivities in the NAc suggests that Cx43 is present in GFAP-containing astrocytes in this brain region. Label "x" indicates the site of ATP application. C: High magnification (scale bar: 20 μm) confocal photomicrograph of a double labelled section of a PFA-fixed rat brain. Yellow colour indicates co-localizations of Cx43 (red) and GFAP (green) immunoreactivities in the PFA-fixed NAc.