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Table 4 Alignment of amino acid sequence in loop D of the agonist binding site of vertebrate and insect nicotinic acetylcholine receptors

From: Mutation of a nicotinic acetylcholine receptor β subunit is associated with resistance to neonicotinoid insecticides in the aphid Myzus persicae

 

Amino Acid Number of Myzus persicae β1 Subunit

Species

77

78

79

80

81

82

83

84

85

86

87

Homo sapiens β2

N

V

W

L

T

Q

E

W

E

D

Y

Gallus gallus β2

N

V

W

L

T

Q

E

W

E

D

Y

Rattus norvegicus β2

N

V

W

L

T

Q

E

W

E

D

Y

Drosophila melanogaster β1

C

V

W

L

R

L

V

W

Y

D

Y

Anopheles gambiae β1

N

V

W

L

R

L

V

W

S

D

Y

Bemisia tabaci β1

N

V

W

L

R

L

V

W

N

D

Y

Locusta migratoria β1

N

V

W

L

R

L

V

W

N

D

Y

Heliothis virescens β1

N

V

W

L

R

L

V

W

M

D

Y

Ctenocephalides felis β1

N

V

W

L

R

L

V

W

S

D

Y

Myzus persicae 4106A β1

N

V

W

L

R

L

V

W

R

D

Y

Myzus persicae 5191A β1

N

V

W

L

R

L

V

W

R

D

Y

Myzus persicae FRC β1

N

V

W

L

T

L

V

W

R

D

Y