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Table 4 Alignment of amino acid sequence in loop D of the agonist binding site of vertebrate and insect nicotinic acetylcholine receptors

From: Mutation of a nicotinic acetylcholine receptor β subunit is associated with resistance to neonicotinoid insecticides in the aphid Myzus persicae

  Amino Acid Number of Myzus persicae β1 Subunit
Species 77 78 79 80 81 82 83 84 85 86 87
Homo sapiens β2 N V W L T Q E W E D Y
Gallus gallus β2 N V W L T Q E W E D Y
Rattus norvegicus β2 N V W L T Q E W E D Y
Drosophila melanogaster β1 C V W L R L V W Y D Y
Anopheles gambiae β1 N V W L R L V W S D Y
Bemisia tabaci β1 N V W L R L V W N D Y
Locusta migratoria β1 N V W L R L V W N D Y
Heliothis virescens β1 N V W L R L V W M D Y
Ctenocephalides felis β1 N V W L R L V W S D Y
Myzus persicae 4106A β1 N V W L R L V W R D Y
Myzus persicae 5191A β1 N V W L R L V W R D Y
Myzus persicae FRC β1 N V W L T L V W R D Y
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