Figure 2

Mean transition frequencies between the three vigilance states in HR, IR and LR mice. The relative amounts of transition frequencies for all vigilance states are plotted separately for L1, L2, D1 and D2. In L2 and D1, the HR animals had significantly more transitions from REMS to WAKE, when compared with both other lines. In D2, the HR line showed a different pattern of transitions for all combinations shown, when compared with IR and LR mice, except for the transition of REMS to NREMS. Statistical differences between the mouse lines are indicated by asterisks (*). Data are given as means ± SEM.