The levels of ET
receptor mRNA (A) and protein (B) expression in rat cerebral arteries. The cerebral arteries were isolated from groups of fresh air, SHS and SHS treatment with GW5074. Receptor mRNA content was examined by real-time PCR (n = 5-8) and the protein level was examined by Western blot (n = 5-6). *P < 0.05, **P < 0.01 versus fresh air group, #P < 0.05 versus SHS group; SHS, secondhand smoke exposure; GW, GW5074 (0.5 mg/kg).