Effect of running exercise on NMDAR availability in wild type and PN-1 -/- mice. (A) Representative immunoblot detecting NR1, NR2A and NR2B NMDAR subunits in hippocampal synaptosomal fraction of WT and PN-1 -/- mice without (CTR) and with running exercise (RUN). (B-E) Quantification of similar immunoblots including AMPA receptor as control. All data are the means of 3 animals. For each treatment, values in the WT without exercise were taken as 100% relative to the actin level.